MyBioSource.com's FPRL1 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, and Western Blot. The FPRL1 Antibody was generated using formyl peptide receptor 2, and FPR2 as the antigen and it reacts with Human, and Mouse.
Description
Description: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).
Similarity: Belongs to the G-protein coupled receptor 1 family